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This study aimed to determine the effect of sdy genotype on motor coordination deficit in mice using rotarod test. We used wild type and sdy genotype mice to conduct the experiment. The mice were tested in a rotarod apparatus with two different trials per day. The number of falls during the first trial was recorded and the latency to fall in seconds from the rotating drum was counted. The results showed that sdy genotype mice had a significantly greater deficit in the rotarod test, indicating impaired locomotor activity and stereotypic behavior.

The results of the experiment are presented in the form of a table. The data were analyzed by one-way repeated measures ANOVA and the genotype effects in each trial were compared. The statistical significance was determined at P 0.05. The authors would like to thank the staff of the Institute of Animal Welfare and Biotechnology for their help and support in carrying out the experiment. The research was supported by a grant from the National Natural Sciences Foundation of China (NSFC) and the Scientific Research Fund for Young Scientists of the Chinese Academy of Sciences. The authors declare no conflict of interest. This article is an open access publication. The full version can be accessed free of charge on the journal’s website. The authors voluntarily contributed the original material to this journal. The manuscript has been reviewed and edited by the journal’s editors and by the publisher. All authors read and approved the final manuscript. The publisher’s policy is to ensure that all publications are rigorously peer-reviewed and the highest scientific standards are maintained. To guarantee this, the publisher accepts submissions only from trusted sources. All submitted articles undergo a stringent peer review process that is overseen by the Editorial Board. This is a vital part of the publisher’s mission to disseminate high quality scientific research. The publisher’s Editorial Board is made up of scientists from around the world who are committed to achieving high standards in peer review. The editorial team are all experts in their respective fields and have extensive experience in reviewing and editing manuscripts. The Editorial Board aims to publish quality papers and welcomes suggestions for improvement from the peer reviewers. The peer review process is rigorous and anonymous.